A DOUBLE BLIND CROSSOVER TRIAL IN PYRIDINOLCARBAMATE TREATMENT OF ATHEROSCLEOSIS OBLITERANS
نویسندگان
چکیده
منابع مشابه
Double-blind crossoer clinical trial of pyridinolcarbamate in peripheral arterial disease (arteriosclerosis obliterans).
A double-blind crossover clinical trial of pyridinolcarbamate, a bradykinin antagonist, was carried out in 33 men with peripheral vascular disease causing intermittent claudication. Results in 25 men are reported. Peripheral circulation was assessed by measurement ofwork done before claudication in a step test, claudication point, and measurement of cal bloodflow by venous occlusion plethysmogr...
متن کاملTreatment of atherosclerosis obliterans with pyridinolcarbamate.
閉塞性動脈硬化症の薬物療法はじゆ うらい比較 的至難なものと考えられてお り,主 として血管拡 張薬が使用 されてきているが,理 論的にはその効 果 も疑問視されている.本 症の主観的症状は四肢 の知覚異常,間歇 性跛行などの症状で始まること が多いが,進 行して皮膚色調の変化,さ らに潰瘍 形成,感 染,壊 疽な どを起こすようになれば,交 感神経切除術,患 部の切断などの外科的処置を行 なわなければならないようにな り,こ の病気の予 後は全 く悲観的である.今 回本症 の75例 にpyri dinolcarbamate治 療を試みて比較的良好な治療成 績が得られたと思われるので,そ の成績について 報告する. 方 法 対 象 は 東 京 医 科 歯 科 大 学 第 三 内 科 の患者 で,総 数75例(男70,女5,年 令24~72才,平 均48.0±1.5 才.,発 病 よ ...
متن کاملNaproxen in osteoarthrosis. Double-blind crossover trial.
In this double-blind crossover trial, naproxen (750 mg/day) was compared to placebo for the treatment of osteoarthrosis of the hip and knee. Patients were randomly assigned to treatment with either naproxen or placebo for 4 weeks and then to treatment with the alternate agent for a second 4-week period. 8 out of 9 objective and subjective measurements of drug efficacy clearly differentiated nap...
متن کاملEffectiveness of Sambucus ebulus Leaf Extract in Treatment of Cutaneous Leishmaniasis: A Double Blind Clinical Trial
Background and purpose: Cutaneous leishmaniasis is a skin disease manifested as chronic ulcerative skin lesions. Current standard therapies for this disease are associated with some problems such as high cost, numerous side effects, need for injections, and drug resistance. Sambucus ebulus is used in treatment of skin inflammation. This study aimed at investigating the effects of S. ebulus leaf...
متن کاملTreatment-Responsiveness of Negative Symptoms in Schizophrenia: A double-blind placebo-control clinical trial
Background: The negative symptoms of schizophrenia remain a major clinical challenge. Nortriptyline is a serotonin and noradrenalin reuptake inhibitor and belongs to secondary amine tricycles. The aim of this study is to evaluate the effect of nortriptyline on the negative symptoms of schizophrenia. Methods: This study is a six-week randomized placebo-control trial of nortriptyline or placebo a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1969
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.58.283